Keywords
pregnancy
screening
levothyroxine
How to Cite
Abstract
Abstract
Thyroid diseases are among the endocrine disorders most frequently reported during pregnancy, in part due to the physiologic changes that occur mainly in the first trimester. In pregnant patients, clinical hypothyroidism has a prevalence of 0.3-1.9%, while subclinical hypothyroidism has a prevalence of 1.5-5%. These percentages depend on different variables such as iodine intake. Hypothyroidism generally represents a risk for the maternal-fetal unit, hence the need for population-based, trimester-specific TSH reference ranges to make an appropriate diagnosis. Treatment consists of oral levothyroxine, aiming for established goals. Furthermore, early detection of patients with risk factors, as well as those with a previous diagnosis of hypothyroidism allows for adequate follow up. Therefore, databases at a regional or national level are required to establish population-based, trimester-specific TSH reference ranges.
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