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Abstract
Neurodegenerative diseases such as Alzheimer’s disease have not been fully understood by the scientific community, which is why multiple studies focused their studies on finding simple non-invasive tests by using biomarkers that are sufficiently sensitive and specific for the early detection of degenerative dementia.
However, extracerebral studies such as serum and plasma specific copper, urine copper, ceruloplasmin, alpha-2-macroglobulin (α2M) and complement factor H (CFH) and other nonspecific tests, which were confirmed with magnetic resonances, have been used for a long time. This fact empathize the need for new standardized biomarkers more specific for these diseases.
Therefore, biomarkers such as ALZAS, RAGE and other autoantibodies detected in the serum of Alzheimer’s patients have been highlighted.
Key words: Hepatocerebral disorders, Alzheimer, biomarkers.
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